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Tincture of iodine, iodine tincture, or weak iodine solution is an antiseptic. It is usually 2 to 3% elemental iodine, along with potassium iodide or sodium iodide, dissolved in a mixture of ethanol and water. Tincture solutions are characterized by the presence of alcohol.
In the alternative, iodine may be produced from iodophors, which contain iodine complexed with a solubilizing agent (the iodide ion may be thought of loosely as the iodophor in triiodide water solutions). Examples of such preparations include: [11] Tincture of iodine: iodine in ethanol, or iodine and sodium iodide in a mixture of ethanol and water.
Iodophors are prepared by mixing iodine with the solubilizing agent; heat can be used to speed up the reaction. Besides povidone, polyvinyl alcohol, starch derivatives (e.g. dextrin forming cadexomer iodine), chitosan and cellulose have also been used as solubilizing agents. [3]
Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. [4] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine. [4] It works by releasing iodine which results in the death of a range of microorganisms. [1]
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