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Long-term treatment with bisphosphonates produces anti-fracture and bone mineral density effects that persist for 3–5 years after an initial 3–5 years of treatment. [2] The bisphosphonate alendronate reduces the risk of hip, vertebral, and wrist fractures by 35-39%; zoledronate reduces the risk of hip fractures by 38% and of vertebral ...
Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [4] Use is often recommended together with vitamin D, calcium supplementation, and lifestyle changes. [4]
Free radical damage within cells has been linked to a range of disorders including cancer, arthritis, atherosclerosis, Alzheimer's disease, and diabetes. [13] There has been some evidence to suggest that free radicals and some reactive nitrogen species trigger and increase cell death mechanisms within the body such as apoptosis and in extreme ...
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5] [6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7]
[5] [6] [11] They do not appear to affect the risk of death. [12] Osteoporosis becomes more common with age. About 15% of Caucasians in their 50s and 70% of those over 80 are affected. [7] It is more common in women than men. [3] In the developed world, depending on the method of diagnosis, 2% to 8% of males and 9% to 38% of females are ...
According to the Arthritis Foundation, glucosamine is one of the most popular supplements for managing arthritic joint pain. Glucosamine is a naturally occurring compound in the body that builds ...
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