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Combining any statin with a fibrate or niacin (other categories of lipid-lowering drugs) increases the risks for rhabdomyolysis to almost 6.0 per 10,000 person-years. [99] Monitoring liver enzymes and creatine kinase is especially prudent in those on high-dose statins or in those on statin/fibrate combinations, and mandatory in the case of ...
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
Examples of this drug class are atorvastatin, rosuvastatin, fluvastatin, simvastatin, pravastatin and lovastatin. Most efficacious in lowering LDL-C levels, statins block the action of HMG-CoA reductase through competitive inhibition. [18]
An alternative to statins may help reduce deaths from heart disease among people with high levels of LDL, or “bad” cholesterol, new research finds.. When taken as a daily pill, bempedoic acid ...
Data collection also did not note the dosage of statin medications, medication adherence, or changes in HDL cholesterol levels. Furthermore, the researchers did not stratify atherosclerotic ...
Statins are widely-used cholesterol-lowering medications that have documented anti-inflammatory properties. Despite the promising findings, the research is still very early and needs to undergo ...
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