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Autoimmune diseases can result in systemic or localized symptoms, depending on the given disease. [8] Typical systemic symptoms include fevers, fatigue, muscle aches, joint pain, and rashes; these can be seen in diseases such as lupus or rheumatoid arthritis. Other autoimmune diseases have localized effects on specific organ or tissue types.
In the case of an autoimmune-induced miscarriage, the woman's body attacks the growing fetus or prevents normal pregnancy progression. [9] [94] Autoimmune disease may cause abnormalities in embryos, which in turn may lead to miscarriage. As an example, coeliac disease increases the risk of miscarriage by an odds ratio of approximately 1.4.
The immune system of the human body is different in the body of a pregnant person, compared to any other human being. Pregnant people are more susceptible to disease, and the idea of even treating these diseases can be risky. Complications caused by treating these diseases can lead to long term damage to the parent, fetus, or both.
Antiphospholipid syndrome: The antiphospholipid syndrome is an autoimmune disease that is a common cause of recurrent pregnancy loss. [34] [15] Around 15% of the women who have recurrent miscarriages have high levels of antiphospholipid antibodies. [34]
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Autoimmune oophoritis is a rare autoimmune disease where the body's own immune system attacks the ovaries. [1] This causes the ovaries to have inflammation, atrophy , and fibrosis . Such changes in the ovaries can cause them to not function properly.
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
A key difference is a malfunction of the innate immune system in autoinflammatory diseases, whereas in autoimmune diseases there is a malfunction of the adaptive immune system. [ 8 ] Symptoms of autoimmune diseases can significantly vary, primarily based on the specific type of the disease and the body part that it affects.