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Bacteria typically enter the lung with inhalation, though they can reach the lung through the bloodstream if other parts of the body are infected. Often, bacteria live in parts of the upper respiratory tract and are continuously being inhaled into the alveoli , the cavities deep in the lungs where gas exchange takes place.
Bacteremia can travel through the blood stream to distant sites in the body and cause infection (hematogenous spread). Hematogenous spread of bacteria is part of the pathophysiology of certain infections of the heart ( endocarditis ), structures around the brain ( meningitis ), and tuberculosis of the spine ( Pott's disease ).
Neutrophils extravasate from blood vessels to the site of tissue injury or infection during the innate immune response.. In immunology, leukocyte extravasation (also commonly known as leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes (white blood cells) out of the circulatory system (extravasation) and towards the ...
Found in E. coli and in chromosomes of other bacteria [29] yafO yafN: A system induced by the SOS response to DNA damage in E. coli [68] hicA hicB: Found in archaea and bacteria [69] kid kis: Stabilises the R1 plasmid and is related to the CcdB/A system [23] ζ ε: Found mostly in Gram-positive bacteria [64] ataT ataR: Found in enterohemorragic ...
An infectious disease agent can be transmitted in two ways: as horizontal disease agent transmission from one individual to another in the same generation (peers in the same age group) [3] by either direct contact (licking, touching, biting), or indirect contact through air – cough or sneeze (vectors or fomites that allow the transmission of the agent causing the disease without physical ...
Tuberculosis of the lungs may also occur via infection from the blood stream. This is known as a Simon focus and is typically found in the top of the lung. [ 91 ] This hematogenous transmission can also spread infection to more distant sites, such as peripheral lymph nodes, the kidneys, the brain, and the bones.
Drugs can increase a person's risk of aspiration through multiple mechanisms. [6] Medications including sedatives, hypnotics, and antipsychotics can result in decreased level of consciousness and loss of cough and swallow reflexes. [7] Long-term use of proton pump inhibitors can lead to overgrowth of gastric bacteria and increase risk of ...
Benzalkonium chloride solutions are fast-acting biocidal agents with a moderately long duration of action. They are active against bacteria and some viruses, fungi, and protozoa. Bacterial spores are considered to be resistant. Solutions are bacteriostatic or bactericidal according to their concentration.