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The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus. It has a basal layer and a functional layer: the basal layer contains stem cells which regenerate the functional layer. [1] The functional layer thickens and then is shed during menstruation in humans and some other mammals, including other ...
Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation. It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material ...
Uterine glands or endometrial glands are tubular glands, lined by a simple columnar epithelium, found in the functional layer of the endometrium that lines the uterus. Their appearance varies during the menstrual cycle. During the proliferative phase, uterine glands appear long due to estrogen secretion by the ovaries.
From innermost to outermost, these layers are the endometrium, myometrium, and perimetrium. [7] The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus. It has a basal layer and a functional layer; the functional layer thickens and then is shed during the menstrual cycle or estrous cycle.
Layer Location Description Cytotrophoblast: The inner layer: A single-celled inner layer of the trophoblast. Syncytiotrophoblast: The outer layer: A thick layer that lacks cell boundaries and grows into the endometrial stroma. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. Intermediate trophoblast (IT)
This layer is absent in placenta accreta. [2] Micrograph of decidualized endometrium due to exogenous progesterone. H&E stain. The decidua has a histologically-distinct appearance, displaying large polygonal decidual cells in the stroma. These are enlarged endometrial stromal cells, which resemble epithelium (and are referred to as "epithelioid").
With cessation of progesterone release, the uterine lining (functional, inner layer of the endometrium) is expelled through the vagina (in mammals that go through a menstrual cycle). Across an estrous cycle, the functional layer regenerates to provide nourishing tissue for potential fertilisation and implantation. [15] [16]
The cavity of the uterus is lined by the endometrium.This lining is composed of two layers, the functional layer (adjacent to the uterine cavity) which is shed during menstruation and an underlying basal layer (adjacent to the myometrium), which is necessary for regenerating the functional layer.