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Researchers have said new stem cell treatment could be used to slow damage to the brain in MS patients Multiple sclerosis stem cell treatment breakthrough could stop disease in its tracks, study finds
A vast amount research has been conducted in recent years for the use of mesenchymal stem cells to treat multiple sclerosis. [ 17 ] [ 18 ] This form of treatment for the disease has been tested in many studies of experimental allergic encephalomyelitis , the animal model of multiple sclerosis, and several published and on-going phase I and ...
Research in multiple sclerosis may find new pathways to interact with the disease, improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis .
Stem cell transplantation was found feasible in a Phase I/II study in 21 patients with relapsing-remitting MS not responsive to interferon beta. It involves collecting some of the patient's own peripheral blood stem cells, giving low-intensity chemotherapy to eliminate auto-reactive lymphocytes, and then reinfusing the stem cells. [62]
[17] [18] [19] The title of his PhD thesis was ‘Development of a neural stem cell-based therapy for experimental multiple sclerosis in mice’. He then completed his post-doctoral research at San Raffaele Scientific Institute, and Vita-Salute San Raffaele University, Milan. He was also an instructor in Experimental Neurosciences at University ...
People with PPMS have also been included in trials of azathioprine, methotrexate, intravenous immunoglobulin, cyclophosphamide [81] and hematopoietic stem cell transplantation. [ 82 ] In March 2017, ocrelizumab was approved in the United States for the treatment of primary progressive multiple sclerosis in adults.
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