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Your body can make creatine on its own, but not close to the levels found in modern supplements. ... so, too, did the rumors that the supplement would damage your kidneys and liver—and might ...
Creatine doesn’t seem to affect kidney function for healthy people, but those with known kidney disorders or dysfunction should steer clear, as it can possibly worsen kidney dysfunction, ...
Creatine is more popular than ever, but is it safe? Here's what you need to know about creatine supplements.
Serum creatinine (a blood measurement) is an important indicator of kidney function, because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced [5] via a biological system involving creatine, phosphocreatine (also known as creatine phosphate), and adenosine ...
It is important to mention that kidneys themselves, for normal physiological function, need phosphocreatine and creatine and indeed kidneys express significant amounts of creatine kinases (BB-CK and u-mtCK isoenzymes). [84] At the same time, the first of two steps for endogenous creatine synthesis takes place in the kidneys themselves.
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.