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  2. Efficacy - Wikipedia

    en.wikipedia.org/wiki/Efficacy

    Efficacy is the ability to perform a task to a satisfactory or expected degree. The word comes from the same roots as effectiveness , and it has often been used synonymously, although in pharmacology a distinction is now often made between efficacy and effectiveness .

  3. Evidence-based design - Wikipedia

    en.wikipedia.org/wiki/Evidence-based_design

    Evidence-based design (EBD) was popularized by the seminal study by Ulrich (1984) that showed the impact of a window view on patient recovery. [3] Studies have since examined the relationships between design of the physical environment of hospitals with outcomes in health, the results of which show how the physical environment can lower the incidence of nosocomial infections, medical errors ...

  4. Outcome measure - Wikipedia

    en.wikipedia.org/wiki/Outcome_measure

    An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment. [1] [2] Measures can often be quantified using effect sizes. [3]

  5. Outcomes research - Wikipedia

    en.wikipedia.org/wiki/Outcomes_research

    Common themes of outcomes research are: Safety. Misuse of medical therapy and oversight in the course of clinical care; Medical mistakes that place patients at risk for adverse events; Effectiveness. The gap between what can be achieved through medical intervention or policy and what is actually accomplished

  6. Clinical study design - Wikipedia

    en.wikipedia.org/wiki/Clinical_study_design

    Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...

  7. Clinical research - Wikipedia

    en.wikipedia.org/wiki/Clinical_research

    Clinical research is different from clinical practice: in clinical practice, established treatments are used to improve the condition of a person, while in clinical research, evidence is collected under rigorous study conditions on groups of people to determine the efficacy and safety of a treatment.

  8. Hierarchy of evidence - Wikipedia

    en.wikipedia.org/wiki/Hierarchy_of_evidence

    A large number of hierarchies of evidence have been proposed. Similar protocols for evaluation of research quality are still in development. So far, the available protocols pay relatively little attention to whether outcome research is relevant to efficacy (the outcome of a treatment performed under ideal conditions) or to effectiveness (the outcome of the treatment performed under ordinary ...

  9. Monitoring in clinical trials - Wikipedia

    en.wikipedia.org/wiki/Monitoring_in_clinical_trials

    Clinical monitoring is the oversight and administrative efforts that monitor a participant's health and efficacy of the treatment during a clinical trial.Both independent and government-run grant-funding agencies, such as the National Institutes of Health (NIH) [1] and the World Health Organization (WHO), [2] require data and safety monitoring protocols for Phase I and II clinical trials ...