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Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. [5] It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. [2] With AS, eye and bowel problems—as well as back pain—may occur. [2]
Spondylitis is an inflammation of the vertebrae. It is a form of spondylopathy . In many cases, spondylitis involves one or more vertebral joints , as well, which itself is called spondylarthritis .
Inflammatory arthritis can sometimes cause symptoms in parts of the body other than the joints, like the eyes, heart, or lungs. ... Ankylosing spondylitis. Lupus arthritis. Juvenile idiopathic ...
Axial spondyloarthritis can be differentiated from peripheral spondyloarthritis in terms of the areas of the body affected. The axial form of the disease primarily affects the spine, pelvis and thoracic cage, whereas the peripheral form mainly targets the arms and legs. [10] Axial spondyloarthritis can be divided into two classes:
Microscopically visible ileal inflammation is seen in about 50% of people with spondyloarthritis and ankylosing spondylitis during ileocolonoscopy. [11] [4] There seems to be an immunological connection between the gut inflammation observed in Crohn's disease and ankylosing spondylitis. [12]
An ocular manifestation of a systemic disease is an eye condition that directly or indirectly results from a disease process in another part of the body. There are many diseases known to cause ocular or visual changes.
In an eye examination, light-colored spots on the retina are seen. Complete loss of visual acuity may happen [ citation needed ] The name of the condition comes from the small light-colored fundus spots on the retina, scattered in a pattern like birdshot from a shotgun , but these spots might not be present in early stages.
It is a feature of spondyloarthropathies, such as axial spondyloarthritis (including ankylosing spondylitis), psoriatic arthritis, reactive arthritis or arthritis related to inflammatory bowel diseases, including ulcerative colitis or Crohn's disease. It is also the most common presentation of arthritis from brucellosis.
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