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An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), "(medicine) given as a remedy". An older term in English which is now rare is atterlothe, derived from "atter" ("poison" or "venom"). [2]
The drug has been used as an antidote in the treatment of benzodiazepine overdoses. [8] It reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine (BZ) recognition site on the GABA/benzodiazepine receptor complex. There are many complications that must be taken into consideration when used in the acute care ...
For example, naloxone is the antidote for opiates such as heroin or morphine. Similarly, benzodiazepine overdoses may be effectively reversed with flumazenil. As a nonspecific antidote, activated charcoal is frequently recommended if available within one hour of the ingestion and the ingestion is significant. [23]
After years of continuously rising opioid overdoses, the US Centers for Disease Control and Prevention reported that overdose deaths decreased 3% in 2023, the first annual decrease since 2018. A ...
Alcohols, in various forms, are used medically as an antiseptic, disinfectant, and antidote. [1] Alcohols applied to the skin are used to disinfect skin before a needle stick and before surgery. [2] They may also be used as a hand sanitizer; [2] to clean other areas; [2] and in mouthwashes.
“I love getting high,” says James “Sleaze” Morgan. But the antidote to fentanyl is a different story. Naloxone abruptly plunges an overdosed user into excruciating withdrawal symptoms, he ...
Sodium thiosulfate is a classical antidote to cyanide poisoning, [10] For this purpose it is used after the medication sodium nitrite and typically only recommended for severe cases. [4] [6] It is given by injection into a vein. [4] In this use, sodium nitrite creates methemoglobinemia which removes cyanide from mitochondria. [6]
It is composed of antibodies and used to treat certain venomous bites and stings. [1] Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. [1] The specific antivenom needed depends on the species involved. [1] It is given by injection. [1] Side effects may be severe. [1]