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In order to obtain spatial information about the gamma-ray emissions from an imaging subject (e.g. a person's heart muscle cells which have absorbed an intravenous injected radioactive, usually thallium-201 or technetium-99m, medicinal imaging agent) a method of correlating the detected photons with their point of origin is required.
The power of prognosis from a myocardial perfusion scan is excellent and has been well tested, and this is "perhaps the area of nuclear cardiology where the evidence is most strong". [ 13 ] [ 16 ] Many radionuclides used for myocardial perfusion imaging, including rubidium-82 , technetium-99m and thallium-201 have similar typical effective ...
Nuclear medicine myocardial perfusion scan with thallium-201 for the rest images (bottom rows) and Tc-Sestamibi for the stress images (top rows). The nuclear medicine myocardial perfusion scan plays a pivotal role in the non-invasive evaluation of coronary artery disease. The study not only identifies patients with coronary artery disease; it ...
Scintigraphy (from Latin scintilla, "spark"), also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by gamma cameras, which are external detectors that form two-dimensional images [1] in a process similar to the ...
Thallium-201 is synthesized by the neutron activation of stable thallium in a nuclear reactor, [18] [19] or by the 203 Tl(p, 3n) 201 Pb nuclear reaction in cyclotrons, as 201 Pb naturally decays to 201 Tl afterwards. [20] It is a radiopharmaceutical, as it has good imaging characteristics without excessive patient radiation dose.
Scanning is time-consuming, and it is essential that there is no patient movement during the scan time. Movement can cause significant degradation of the reconstructed images, although movement compensation reconstruction techniques can help with this. A highly uneven distribution of radiopharmaceutical also has the potential to cause artifacts.
Sodium iodide (NaI) containing a small amount of thallium is used as a scintillator for the detection of gamma waves and zinc sulfide (ZnS) is widely used as a detector of alpha particles. Zinc sulfide is the material Rutherford used to perform his scattering experiment.
One frame of an MRI scan of the head showing the eyes and brain A magnetic resonance imaging instrument ( MRI scanner ), or "nuclear magnetic resonance ( NMR ) imaging" scanner as it was originally known, uses powerful magnets to polarize and excite hydrogen nuclei (i.e., single protons ) of water molecules in human tissue, producing a ...