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Pages in category "Organophosphate insecticides" The following 68 pages are in this category, out of 68 total. This list may not reflect recent changes. A.
Organophosphate insecticides are acetylcholinesterase inhibitors, which disrupt the transmission of nerve signals in exposed organisms, with fatal results. The risk of human death through organophosphate poisoning [ 32 ] was obvious from the start and led to efforts to lower toxicity against mammals while not reducing efficacy against insects.
Organophosphate insecticides (68 P) Organophosphate nerve agents (3 C, 5 P) Organophosphorohalidates (1 C, 1 P) Organophosphoropseudohalidates (1 P) P. Phospholipids ...
A variety of mixed amido-alkoxo derivatives are known, one medically significant example being the anti-cancer drug cyclophosphamide. Also derivatives containing the thiophosphoryl group (P=S) include the pesticide malathion. The organophosphates prepared on the largest scale are the zinc dithiophosphates, as additives for motor oil.
These compounds are the basis of antisense therapy, e.g., the drugs fomivirsen (Vitravene), oblimersen, alicaforsen, and mipomersen (Kynamro). [2] Further examples of these include: Diazinon; Fenitrothion; Fenthion; Thiotepa; Variants with P=S double bonds were developed as insecticides because of their reduced mammalian toxicity.
Dimethoate is a widely used organophosphate insecticide and acaricide. It was patented and introduced in the 1950s by American Cyanamid. Like other organophosphates, dimethoate is an acetylcholinesterase inhibitor which disables cholinesterase, an enzyme essential for central nervous system function. It acts both by contact and through ingestion.