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  2. Dr. Hersh: Glioblastoma is the most common and aggressive ...

    www.aol.com/dr-hersh-glioblastoma-most-common...

    Glioblastoma (GBM) is the most common and aggressive malignant brain tumor, accounting for about 15% of all primary malignant brain tumors.

  3. Glioblastoma - Wikipedia

    en.wikipedia.org/wiki/Glioblastoma

    Surgery is the first stage of treatment of glioblastoma. An average GBM tumor contains 10 11 cells, which is on average reduced to 10 9 cells after surgery (a reduction of 99%). Benefits of surgery include resection for a pathological diagnosis, alleviation of symptoms related to mass effect, and potentially removing disease before secondary ...

  4. Temozolomide - Wikipedia

    en.wikipedia.org/wiki/Temozolomide

    Temozolomide is an alkylating agent used to treat serious brain cancers; most commonly as second-line treatments for astrocytoma and as the first-line treatment for glioblastoma. [ 4 ] [ 6 ] [ 7 ] Olaparib in combination with temozolomide demonstrated substantial clinical activity in relapsed small cell lung cancer . [ 8 ]

  5. Multiple endocrine neoplasia - Wikipedia

    en.wikipedia.org/wiki/Multiple_endocrine_neoplasia

    Multiple endocrine neoplasia (abbreviated MEN) is a condition which encompasses several distinct syndromes featuring tumors of endocrine glands, each with its own characteristic pattern. In some cases, the tumors are malignant, in others, benign. Benign or malignant tumors of nonendocrine tissues occur as components of some of these tumor ...

  6. What is glioblastoma? McCain’s brain tumor is an ... - AOL

    www.aol.com/news/2017-07-20-what-is-glioblastoma...

    John McCain suffers from a highly malignant form of cancer that spreads quickly due to its association with a large network of blood vessels in the brain. What is glioblastoma? McCain’s brain ...

  7. Giant-cell glioblastoma - Wikipedia

    en.wikipedia.org/wiki/Giant-cell_glioblastoma

    The giant-cell glioblastoma is a histological variant of glioblastoma, presenting a prevalence of bizarre, multinucleated (more than 20 nuclei) giant (up to 400 μm diameter) cells. It occasionally shows an abundant stromal reticulin network and presents a high frequency of TP53 gene mutations .