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  2. New York Heart Association Functional Classification

    en.wikipedia.org/wiki/New_York_Heart_Association...

    The New York Heart Association (NYHA) Functional Classification provides a simple way of classifying the extent of heart failure.It places patients in one of four categories based on how much they are limited during physical activity; the limitations/symptoms are in regard to normal breathing and varying degrees in shortness of breath and/or angina.

  3. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    The NYHA functional classes (I–IV) begin with class I, which is defined as a person who experiences no limitation in any activities and has no symptoms from ordinary activities. People with NYHA class II heart failure have slight, mild limitations with everyday activities; the person is comfortable at rest or with mild exertion.

  4. Implantable cardioverter-defibrillator - Wikipedia

    en.wikipedia.org/wiki/Implantable_cardioverter...

    With Left Ventricular Ejection Fraction (LVEF) ≤ 35% due to prior Myocardial Infarction (MI) who are at least 40 days post-MI and are in NYHA Functional Class II or III; With Left Ventricular (LV) dysfunction due to prior MI who are at least 40 days post-MI, have an LVEF ≤ 30%, and are in NYHA Functional Class I

  5. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    AICD: Patients with NYHA class II, III or IV, and LVEF of 35% (without a QRS requirement) may also benefit from an implantable cardioverter-defibrillator (ICD), a device that is proven to reduce all-cause mortality by 23% compared to placebo in patients who were already optimally managed on drug therapy.

  6. Mitral stenosis - Wikipedia

    en.wikipedia.org/wiki/Mitral_stenosis

    Mitral stenosis typically progresses slowly (over decades) from the initial signs of mitral stenosis to NYHA functional class II symptoms to the development of atrial fibrillation to the development of NYHA functional class III or IV symptoms. Once an individual develops NYHA class III or IV symptoms, the progression of the disease accelerates ...

  7. Lisinopril - Wikipedia

    en.wikipedia.org/wiki/Lisinopril

    Based on urinary recovery, the mean extent of absorption of lisinopril is approximately 25% (reduced to 16% in people with New York Heart Association Functional Classification (NYHA) Class II–IV heart failure), with large interpatient variability (6 to 60%) at all doses tested (5 to 80 mg).

  8. Brain natriuretic peptide 32 - Wikipedia

    en.wikipedia.org/wiki/Brain_natriuretic_peptide_32

    4879 18158 Ensembl ENSG00000120937 ENSMUSG00000029019 UniProt P16860 P40753 RefSeq (mRNA) NM_002521 NM_001287348 NM_008726 RefSeq (protein) NP_002512 NP_002512 NP_001274277 NP_032752 Location (UCSC) Chr 1: 11.86 – 11.86 Mb Chr 4: 148.07 – 148.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone ...

  9. Cardiac contractility modulation - Wikipedia

    en.wikipedia.org/wiki/Cardiac_contractility...

    The FDA approved the OPTIMIZER Smart System, which delivers cardiac contractility modulation therapy, as indicated to improve 6-minute hall walk distance, quality of life, and functional status of NYHA Class III heart failure patients who remain symptomatic despite guideline directed medical therapy, who are in normal sinus rhythm, are not indicated for cardiac resynchronization therapy, and ...