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Postherpetic neuralgia (PHN) is neuropathic pain that occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles). Typically, the nerve pain (neuralgia) is confined to an area of skin innervated by a single sensory nerve, which is known as a dermatome. PHN is ...
The vaccine reduced rates of persistent, severe pain after shingles by 66% in people who contracted shingles despite vaccination. [59] Vaccine efficacy was maintained through four years of follow-up. [59] It has been recommended that people with primary or acquired immunodeficiency should not receive the live vaccine. [59]
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After it subsides, it stays dormant in nerve cells in the body. It may reactivate under conditions of physiological stress or if the immune system is suppressed in any way (for example during an illness or undergoing chemotherapy), resulting in herpes zoster, also known as shingles or Ramsay Hunt syndrome when facial paralysis in involved. If ...
Shingles can lead to serious problems such as deafness, long-lasting pain, and blindness.
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [8] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
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