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The choice of antiarthritic medication is often determined by the nature of arthritis, the severity of symptoms as well as other factors, such as the tolerability of side effects. A dorsal view of the hand, revealed swelling of the finger joints, indicative of an underlying inflammatory process at the proximal interphalangeal joints
Osteoarthritis commonly affects three main sites in the hand: the base of the thumb, where the thumb and wrist converge, known as the carpometacarpal (CMC) joint; the joint closest to the fingertip, referring to the distal interphalangeal joint (DIP); the middle joint of a finger, referring to the proximal interphalangeal joint (PIP). [5 ...
Osteoarthritis commonly affects the hands, feet, spine, and the large weight-bearing joints, such as the hips and knees, although in theory, any joint in the body can be affected. As osteoarthritis progresses, movement patterns (such as gait ), are typically affected. [ 1 ]
Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [ 3 ] and synovial villous proliferation are often seen.
Jaccoud arthropathy (JA), is a chronic non-erosive reversible joint disorder that may occur after repeated bouts of arthritis. [1] [2] It is caused by inflammation of the joint capsule and subsequent fibrotic retraction, causing ulnar deviation of the fingers, through metacarpophalangeal joint (MCP) subluxation, [1] [3] primarily of the ring and little-finger. [3]
Several approved drugs are being investigated as repurposed agents in the treatment of osteoarthritis such as liraglutide (anti-diabetic and anti-obesity drug: NCT02905864), Metformin (anti-diabetic drug: NCT04767841, NCT05034029), Zoledronic acid (anti-osteoporotic drug: NCT04303026), etc. [4] Paroxetine has been deemed to have DMOAD activity ...
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