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[1] [7] An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. [1] The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain, and upper abdominal pain that improves with eating. [1] With a gastric ulcer, the pain may worsen with eating. [8]
Diagnosis is generally made by endoscopy with biopsy to evaluate histology. Review of symptoms and associated conditions is important. Review of symptoms and associated conditions is important. Treatment
In many cases, gastrinoma is diagnosed based on the patient's history which is typically characterized by recurrent episodes of peptic ulcer disease or by severe reflux esophagitis and/or diarrhea or by acid-related symptoms which fail to respond to standard treatment regimens. [16]
Most people infected with H. pylori never experience any symptoms or complications, but will have a 10% to 20% risk of developing peptic ulcers or a 0.5% to 2% risk of stomach cancer. [ 8 ] [ 65 ] H. pylori induced gastritis may present as acute gastritis with stomach ache , nausea , and ongoing dyspepsia (indigestion) that is sometimes ...
The duodenal bulb is the site of duodenal ulcer occurrence. Duodenal ulcers are more common than gastric ulcers and - unlike gastric ulcers - are caused by increased gastric acid secretion. Duodenal ulcers are commonly located anteriorly, and rarely posteriorly. Anterior ulcers can be complicated by perforation, while the posterior ones bleed.
Zollinger–Ellison syndrome. Zollinger–Ellison syndrome (Z-E syndrome) is rare disease in which tumors cause the stomach to produce too much acid, resulting in peptic ulcers. Symptoms include abdominal pain and diarrhea. The syndrome is caused by a gastrinoma, a neuroendocrine tumor that secretes a hormone called gastrin. [2]
Any ulcers discovered during the evaluation should be treated in standard fashion. Severe disease with persistent and substantial protein loss despite cetuximab may require total removal of the stomach , especially when the disease is debilitating or irretractable or when there is a high risk for developing gastric cancer. [ 8 ]
Gastric ulcer. This is a timeline of the events relating to the discovery that peptic ulcer disease and some cancers are caused by H. pylori. In 2005, Barry Marshall and Robin Warren were awarded the Nobel Prize in Physiology or Medicine for their discovery that peptic ulcer disease (PUD) was primarily caused by Helicobacter pylori, a bacterium ...