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Packing problems are a class of optimization problems in mathematics that involve attempting to pack objects together into containers. The goal is to either pack a single container as densely as possible or pack all objects using as few containers as possible. Many of these problems can be related to real-life packaging, storage and ...
An overlapping gene (or OLG) [1][2] is a gene whose expressible nucleotide sequence partially overlaps with the expressible nucleotide sequence of another gene. [3] In this way, a nucleotide sequence may make a contribution to the function of one or more gene products. Overlapping genes are present in and a fundamental feature of both cellular ...
The overlap extension polymerase chain reaction (or OE-PCR) is a variant of PCR. It is also referred to as Splicing by overlap extension / Splicing by overhang extension (SOE) PCR. It is used assemble multiple smaller double stranded DNA fragments into a larger DNA sequence. OE-PCR is widely used to insert mutations at specific points in a ...
A contig (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA. [1] In bottom-up sequencing projects, a contig refers to overlapping sequence data (); [2] in top-down sequencing projects, contig refers to the overlapping clones that form a physical map of the genome that is used to guide sequencing and assembly. [3]
The most efficient way to pack different-sized circles together is not obvious. In geometry, circle packing is the study of the arrangement of circles (of equal or varying sizes) on a given surface such that no overlapping occurs and so that no circle can be enlarged without creating an overlap. The associated packing density, η, of an ...
Data striping. In computer data storage, data striping is the technique of segmenting logically sequential data, such as a file, so that consecutive segments are stored on different physical storage devices. An example of data striping. Files A and B, of four blocks each are spread over disks D1 to D3. Striping is useful when a processing ...
Sphere packing finds practical application in the stacking of cannonballs. In geometry, a sphere packing is an arrangement of non-overlapping spheres within a containing space. The spheres considered are usually all of identical size, and the space is usually three- dimensional Euclidean space. However, sphere packing problems can be ...
Spatial Transcriptomics is the ability to capture the positional context of transcriptional activity within intact tissue, either for regions or single cells. When a tissue cryosection is attached to a spatial transcriptomic slide the barcoded primers bind and capture adjacent mRNAs from the tissue.