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  2. Thyroid hormone binding ratio - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormone_binding_ratio

    Thyroid hormone binding ratio (THBR) is a thyroid function test that measures the "uptake" of T3 or T4 tracer by thyroid-binding globulin (TBG) in a given serum sample. This provides an indirect and reciprocal estimate of the available binding sites on TBG within the sample. The results are then reported as a ratio to normal serum.

  3. Thyroxine-binding globulin - Wikipedia

    en.wikipedia.org/wiki/Thyroxine-binding_globulin

    Due to the very low concentration of T 4 and T 3 in the blood, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T 4 /T 3. TBG is synthesized primarily in the liver as a 54-kDa protein. In terms of genomics, TBG is a serpin; however, it has no inhibitory function like many ...

  4. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    Thyroid hormone uptake (T uptake or T 3 uptake) is a measure of the unbound thyroxine binding globulins in the blood, that is, the TBG that is unsaturated with thyroid hormone. [2] Unsaturated TBG increases with decreased levels of thyroid hormones. It is not directly related to triiodothyronine, despite the name T 3 uptake. [2] Reference ranges:

  5. Euthyroid sick syndrome - Wikipedia

    en.wikipedia.org/wiki/Euthyroid_sick_syndrome

    Decreased thyroxine-binding globulin occurs following bypass surgery, and in chronic illness, a less effective form of TBG with lower affinity for thyroxine is synthesized. Reduced quantities of bound thyroid result, leading to decreased total thyroid measurements.

  6. Triiodothyronine - Wikipedia

    en.wikipedia.org/wiki/Triiodothyronine

    Thyroxine-binding globulin (TBG) is a glycoprotein that has a higher affinity for T 4 than for T 3. Transthyretin is also a glycoprotein, but only carries T 4, with hardly any affinity at all for T 3. Finally, both hormones bind with a low affinity to serum albumin, but, due to the large availability of albumin, it has a high capacity.

  7. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.

  8. ‘Bad Blood’ song lyrics meaning: Who is Taylor Swift singing ...

    www.aol.com/news/bad-blood-song-lyrics-meaning...

    Taylor Swift is known for writing autobiographical lyrics about specific people that are or used to be in her orbit. In her song “Bad Blood,” she sends a vindictive message to an ex-friend who ...

  9. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    The major form of thyroid hormone in the blood is thyroxine (T 4), whose half-life of around one week [4] is longer than that of T 3. [5] In humans, the ratio of T 4 to T 3 released into the blood is approximately 14:1. [6] T 4 is converted to the active T 3 (three to four times more potent than T 4) within cells by deiodinases (5′-deiodinase).

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