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Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine.
Esophageal diseases can derive from congenital conditions, or they can be acquired later in life.. Many people experience a burning sensation in their chest occasionally, caused by stomach acids refluxing into the esophagus, normally called heartburn.
Whether esophageal inlet patches may cause other symptoms, such as chronic cough or laryngitis, is unclear. [1] Occasionally, esophageal inlet patches may be seen during a barium esophagram. [3] Findings may include an irregular outline or indentation suggestive of an inlet patch. [3]
Jordan Turko noticed a hoarse voice and back pain. Scans revealed a tumor in his chest and tumors along his spine. A 30-year-old's hoarse voice and back pain turned out to be lung cancer
Esophageal cancer is the eighth-most frequently-diagnosed cancer worldwide, [2] and because of its poor prognosis, it is the sixth most-common cause of cancer-related deaths. [55] It caused about 400,000 deaths in 2012, accounting for about 5% of all cancer deaths (about 456,000 new cases were diagnosed, representing about 3% of all cancers).
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But predicting which patients' cancer will come back as Stage 4 can be challenging. ... Later-stage cancers have already spread to the lymph nodes, are more likely to cause a larger tumor, and ...
Barrett's esophagus – intestinal metaplasia (changes of the epithelial cells from squamous to intestinal columnar epithelium) of the distal esophagus [20] Esophageal adenocarcinoma – a form of cancer [17] GERD sometimes causes injury of the larynx (LPR). [21] [22] Other complications can include aspiration pneumonia. [23]