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Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis.
AbbVie Inc. is an American pharmaceutical company headquartered in North Chicago, Illinois.It is ranked sixth on the list of largest biomedical companies by revenue.In 2023, the company's seat in Forbes Global 2000 was 74, [2] and rank 89 on the 2024 list. [3]
Humira 19 936 18427 3 apixaban: anticoagulant: Eliquis 9872 7395 4 lenalidomide: multiple myeloma: Revlimid 9685 8187 5 nivolumab: oncology: Opdivo 7570 5763 6 pembrolizumab: oncology: Keytruda 7171 3809 7 etanercept: rheumatoid arthritis: Enbrel 7126 7885 8 trastuzumab: breast cancer: Herceptin 6981 7013 9 bevacizumab: colon cancer: Avastin ...
Humira, the brand name of adalimumab, is an anti-TNF antibody discovered by CAT as D2E7, then developed in the clinic and marketed by Abbvie, formerly Abbott Laboratories. CAT was also behind belimumab , the anti-BlyS antibody drug marketed as Benlysta and the first new approved drug for systemic lupus in more than 50 years. [ 1 ]
HUMIRA, an antibody to TNF alpha, was the world's first fully human antibody, [36] which went on to become the world's top selling pharmaceutical with sales of over $18Bn in 2017 [37] Cambridge Antibody Technology was acquired by AstraZeneca in 2006 for £702m.
From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).
Although the use of the term DMARDs was first propagated in rheumatoid arthritis (hence their name), the term has come to pertain to many other diseases, such as Crohn's disease, lupus erythematosus, Sjögren syndrome, immune thrombocytopenic purpura, myasthenia gravis, sarcoidosis, and various others.
Adalimumab (Humira) is an example of an antibody approved for human therapy that was created through phage display. [ 13 ] [ 14 ] Antibodies from human patients or vaccine recipients
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