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Saline solution for irrigation. Normal saline (NSS, NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, 308 mOsm/L or 9.0 g per liter. Less commonly, this solution is referred to as physiological saline or isotonic saline (because it is approximately isotonic to blood serum, which makes it a physiologically normal solution).
Hypertonic Saline which contains sodium chloride works in regulating ICP, intravascular volume and cardiac output without causing significant diuresis, but there are theoretical side effects ranging from neurological complications to subdural hematoma. Hypertonic saline solution has been choice of neuro critical care for the past few years. [1]
Nebulized hypertonic saline has been shown to reduce length of hospitalization and reduce clinical severity in infants with viral bronchiolitis. A possible mechanism is reduced airway edema and mucus plugging to decrease airway obstruction.
Guidelines recommend against the use of nebulized hypertonic saline in the emergency department for children with bronchiolitis but it may be given to children who are hospitalized. [9] [15] Nebulized hypertonic saline (3%) has limited evidence of benefit and previous studies lack consistency and standardization.
In medicine, a nebulizer (American English) [1] or nebuliser (British English) [2] is a drug delivery device used to administer medication in the form of a mist inhaled into the lungs. Nebulizers are commonly used for the treatment of asthma , cystic fibrosis , COPD and other respiratory diseases or disorders.
Nasal irrigation (also called nasal lavage, nasal toilet, or nasal douche) is a personal hygiene practice in which the nasal cavity is washed to flush out mucus and debris from the nose and sinuses, in order to enhance nasal breathing.
Regular use of hypertonic saline nebulizers [5] Low dose inhaled steroids may help decrease airway inflammation and swelling [5] Inhaled Ipratropium may help decrease secretions and stiffen smaller airways [5] Antibiotics during active respiratory infection may decrease severity and length of symptoms [5]
NeilMed Pharmaceuticals was founded by Ketan C. Mehta, [6] [7] a pulmonary and critical-care physician, and Nina Mehta in the year 2000. [8] [9] [10] It started as a side project in 1999 to build a device that could be used to effectively and naturally rinse the sinuses for sinusitis sufferers known as NeilMed Sinus Rinse.