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Cutis marmorata telangiectatica congenita (CMTC) is a rare congenital vascular disorder that usually manifests in affecting the blood vessels of the skin. The condition was first recognized and described in 1922 by Cato van Lohuizen, [2] a Dutch pediatrician whose name was later adopted in the other common name used to describe the condition – Van Lohuizen syndrome.
Cutis marmorata (from Latin marmor, "marble") is a benign skin condition which, if persistent, occurs in Cornelia de Lange syndrome, trisomy 13 and trisomy 18 syndromes. [1] When a newborn infant is exposed to low environmental temperatures, an evanescent , lacy, reticulated red and/or blue cutaneous vascular pattern appears over most of the ...
This disorder was recognized as a distinct syndrome in 1997 and named macrocephaly-cutis marmorata telangiectasia congenita or M-CMTC. [12] [13] A new name, macrocephaly-capillary malformation, abbreviated M-CM, was recommended in 2007. [14] This new name was chosen to more accurately describe the skin markings associated with this disorder.
The skin is frequently observed to have a mottled appearance (cutis marmorata telangiectatica congenita). Other congenital anomalies, including cardiovascular malformations , cleft lip and/or palate , abnormal renal system , and neurologic disorders manifesting as seizure disorders and developmental delay are sometimes observed.
Claudius Galen Guesses At It. Perhaps the most famous doctor to come out of the Roman empire, Claudius Galen acknowledges the clitoris and theorizes that “all the parts, then, that men have, women have too, the difference between them lying in only one thing, namely, that in women the parts are within, whereas in men they are outside.”
Type 5: CMTC (Cutis marmorata telangiectatica congenita) + dermal melanocytosis They all can contain capillary malformation. Type 2 is the most common and can be associated with granular cell tumor.
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