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Posterior circulation infarct (POCI) is a type of cerebral infarction affecting the posterior circulation supplying one side of the brain.. Posterior circulation stroke syndrome (POCS) refers to the symptoms of a patient who clinically appears to have had a posterior circulation infarct, but who has not yet had any diagnostic imaging (e.g. CT Scan) to confirm the diagnosis.
The posterior circulation supplies the medulla, pons, midbrain, cerebellum and (in 70-80% of people) supplies the posterior cerebellar artery to the thalamus and occipital cortex. [1] As a result, symptoms vary widely depending which brain region is predominantly affected. The term 'vertebrobasilar insufficiency' may be used to describe disease ...
Advanced age is one of the most significant stroke risk factors. 95% of stroke occurs in people age 45 and older, and two-thirds of stroke occurs in those over the age of 65. [53] [230] A person's risk of dying if he or she does have stroke also increases with age. However, stroke can occur at any age, including in childhood. [citation needed]
Lateral medullary syndrome is the most common form of posterior ischemic stroke syndrome. It is estimated that there are around 600,000 new cases of this syndrome in the United States alone. [5] [outdated statistic] Those at the overall highest risk for
It occurs more often in males and older people. [2] About 44% of those affected die within a month. [2] A good outcome occurs in about 20% of those affected. [2] Intracerebral hemorrhage, a type of hemorrhagic stroke, was first distinguished from ischemic strokes due to insufficient blood flow, so called "leaks and plugs", in 1823. [6]
[48] [51] [52] MSC treatment also appears to improve the control of cerebral blood flow and blood–brain barrier permeability, [53] [54] as well as what is currently thought to be the most important mechanism of MSC treatment after stroke, the activation of endogenous neuroprotection and neurorestoration pathways by the release of cytokines ...