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The scorpion is perceived both as an embodiment of evil and a protective force such as a dervish's powers to combat evil. [10] In another context, the scorpion portrays human sexuality. [10] Scorpions are used in folk medicine in South Asia, especially in antidotes for scorpion stings. [10]
NTX accounts for only about 1% of the scorpion venom. [7] NTX is one of the best-studied toxic peptides from scorpion venoms. [6] It was the second purified toxin obtained from the genus Centruroides after neurotoxin II [8] and the first short peptide from scorpion venom to be reported in the literature. [9]
The crude venom of T. serrulatus contains different toxins. Some of the strongest derivates are the neurotoxins tityustoxin and toxin Ts-g. [3] Two types of toxins are considered to be responsible for the main toxic effect: toxin gamma (a β-type toxin) and tityustoxin (TsTX, an α-type toxin), both with a specific affinity to the sodium channel. [4]
The deathstalker is one of the most dangerous species of scorpions. [10] [11] Its venom is a powerful mixture of neurotoxins, with a low lethal dose. [12]While a sting from this scorpion is extraordinarily painful, it normally would not kill a healthy adult human.
The pain of a sting from the Arizona Bark Scorpion has been compared to being struck by a bolt of lightning or electrical current. [6] These symptoms may become visible 4 to 7 minutes after injection of venom. Envenomation of a human by a scorpion may affect the sympathetic or parasympathetic systems depending on the species of scorpion.
Scorpion toxins are proteins found in the venom of scorpions.Their toxic effect may be mammal- or insect-specific and acts by binding with varying degrees of specificity to members of the Voltage-gated ion channel superfamily; specifically, voltage-gated sodium channels, voltage-gated potassium channels, [3] and Transient Receptor Potential (TRP) channels.
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Centruroides exilicauda use venom to hunt by injecting the prey which immobilizes or kills it. Their venom has the potential to be fatal to humans. However, the chances of this happening are low. [5] Each scorpion species’ venom has a unique chromatographic profile, due to genetic factors distinct in each species.