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Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]
During long-term use, labetalol can reduce heart rate during exercise while maintaining cardiac output by an increase in stroke volume. [24] Labetalol possesses significant intrinsic sympathomimetic activity (ISA). [2] [22] In particular, it is a partial agonist at β 2-adrenergic receptors located in the vascular smooth muscle.
Group of pharmaceuticals that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia. Type I ( sodium channel blockers)
Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia.
The progress in β-blocker development led to the introduction of drugs with variety of properties. β-blockers were developed having a relative selectivity for cardiac β1-receptors (for example metoprolol and atenolol), partial adrenergic agonist activity , concomitant α-adrenergic blocking activity (for example labetalol and carvedilol) and ...
Finally, in drugs with both alpha and beta blocking properties, such as carvedilol and labetalol, interactions with other alpha or beta blockers can exaggerate a decrease in blood pressure. [2] Conversely, there are also drug interactions with carvedilol or labetalol in which blood pressure is increased unintentionally (such as with cough and ...
Intensive blood pressure control for adults with hypertension and high cardiovascular risk can reduce the risk of mild cognitive impairment, and possibly dementia, in the long term, a new study ...
The mixed alpha-and beta blocker labetalol is especially useful for treatment of concomitant tachycardia and hypertension induced by methamphetamine. [51] The phenomenon of "unopposed alpha stimulation" has not been reported with the use of beta blockers for treatment of methamphetamine toxicity. [51]