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Spatial ecology of soil microorganisms is a function of their chemotactic sensitivities towards substrate and fellow organisms. [74] [non-primary source needed] [non-primary source needed] The chemotactic behavior of the bacteria was proven to lead to non-trivial population patterns even in the absence of environmental heterogeneities. The ...
In general, the most important requisite is to calibrate the incubation time of the assay both to the model cell and the ligand to be evaluated. Too short incubation time results in no cells in the sample, while too long time perturbs the concentration gradients and measures more chemokinetic than chemotactic responses.
Within this medical field is a special reversal form of drug delivery called chemotactic drug targeting. [ 1 ] [ 2 ] By using chemical agents to help guide a drug carrier to a specific location within the body, this innovative approach seeks to improve precision and control during the drug delivery process, decrease the risk of toxicity, and ...
Chemokines (from Ancient Greek χῠμείᾱ (khumeíā) 'alchemy' and κῑ́νησῐς (kī́nēsis) 'movement'), or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells.
By chemotactic selection we can determine whether a still not characterized molecule acts via the long- or the short-term receptor pathway. Recent results proved that chemokines (e.g. IL-8 , RANTES ) are working on long-term chemotaxis receptors, while vasoactive peptides (e.g. endothelin ) act more on the short-term ones.
N-Formylmethionyl-leucyl-phenylalanine (fMLF, fMLP or N-formyl-met-leu-phe) is an N-formylated tripeptide and sometimes simply referred to as chemotactic peptide is a potent polymorphonuclear leukocyte (PMN) chemotactic factor and is also a macrophage activator.
The mechanism of the chemorepulsion of immune cells was first acknowledged by medical researchers at the Massachusetts General Hospital in Boston in early 2002. [1] The phenomenon was originally referred to as "reverse chemotaxis ," and later, “fugetaxis” (derived from the Latin words fugere , to flee from; and taxis , movement). [ 1 ]
In cellular biology, haptotaxis (from Greek ἅπτω (hapto) 'touch, fasten' and τάξις (taxis) 'arrangement, order') is the directional motility or outgrowth of cells, e.g. in the case of axonal outgrowth, usually up a gradient of cellular adhesion sites or substrate-bound chemoattractants (the gradient of the chemoattractant being expressed or bound on a surface, in contrast to the ...