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Mitochondria may have a number of different shapes. [24] A mitochondrion contains outer and inner membranes composed of phospholipid bilayers and proteins. [20] The two membranes have different properties. Because of this double-membraned organization, there are five distinct parts to a mitochondrion: The outer mitochondrial membrane,
Mitochondria are surrounded by two membranes; the inner and outer mitochondrial membranes. These two membranes allow the formation of two aqueous compartments, which are the intermembrane space (IMS) and the matrix. [2] Channel proteins called porins in the outer membrane allow free diffusion of ions and small proteins about 5000 daltons or ...
For typical liver mitochondria, the area of the inner membrane is about 5 times as large as the outer membrane due to cristae. This ratio is variable and mitochondria from cells that have a greater demand for ATP, such as muscle cells, contain even more cristae.
The membrane only allows nonpolar molecules such as CO 2 and O 2 and small non charged polar molecules such as H 2 O to enter the matrix. Molecules enter and exit the mitochondrial matrix through transport proteins and ion transporters. Molecules are then able to leave the mitochondria through porin. [9]
The mitochondria-associated ER membranes (MAMs), play role in cell death modulation. Mitochondrial outer membrane permeabilization (MOMP), is a reason of the higher matrix Ca 2+ levels, which is acts as a trigger for apoptosis. MOMP is the process before apoptosis, which is accompanied to permeability of the inner membrane of the mitochondria ...
A crista (/ ˈ k r ɪ s t ə /; pl.: cristae) is a fold in the inner membrane of a mitochondrion.The name is from the Latin for crest or plume, and it gives the inner membrane its characteristic wrinkled shape, providing a large amount of surface area for chemical reactions to occur on.
Eukaryotic cells have a variety of internal membrane-bound structures, called organelles, and a cytoskeleton which defines the cell's organization and shape. The nucleus stores the cell's DNA , which is divided into linear bundles called chromosomes ; [ 19 ] these are separated into two matching sets by a microtubular spindle during nuclear ...
The two membranes also vary in membrane potential and pH. [3] These factors play a role in the function of mitochondrial membrane transport proteins. There are 53 discovered human mitochondrial membrane transporters, [4] with many others that are known to still need discovered.