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  2. Hypercalcaemia - Wikipedia

    en.wikipedia.org/wiki/Hypercalcaemia

    Even if small amounts are ingested over long periods of time, the prolonged high levels of calcium ions have large negative effects on the animals. [30] The issues these animals experience are muscle weakness, and calcification of blood vessels, heart valves, liver, kidneys, and other soft tissues, which eventually can lead to death.

  3. Calcium in biology - Wikipedia

    en.wikipedia.org/wiki/Calcium_in_biology

    The US Institute of Medicine (IOM) established Recommended Dietary Allowances (RDAs) for calcium in 1997 and updated those values in 2011. [6] See table. The European Food Safety Authority (EFSA) uses the term Population Reference Intake (PRIs) instead of RDAs and sets slightly different numbers: ages 4–10 800 mg, ages 11–17 1150 mg, ages 18–24 1000 mg, and >25 years 950 mg. [10]

  4. Bowditch effect - Wikipedia

    en.wikipedia.org/wiki/Bowditch_effect

    The sodium-calcium exchanger (which allows 3 Na + to flow down its electrochemical gradient in exchange for 1 Ca ++ ion to flow out of the cell) works to decrease the levels of intracellular calcium. As the heart rate becomes more robust, and the length of diastole decreases, the Na + /K +-ATPase, which removes the Na + brought into the cell by ...

  5. Hypertension - Wikipedia

    en.wikipedia.org/wiki/Hypertension

    For people who have never experienced cardiovascular disease who are at a 10-year risk of cardiovascular disease of less than 10%, the 2017 American Heart Association guidelines recommend medications if the systolic blood pressure is >140 mmHg or if the diastolic BP is >90 mmHg. [6]

  6. Here Are Cardiologist-Approved Ways to Lower Your Resting ...

    www.aol.com/cardiologist-approved-ways-lower...

    Science & Tech. Sports. Weather. 24/7 ... some medications for thyroid conditions and migraines can also affect your resting heart rate,” she notes. ... If your heart rate is excessively high or ...

  7. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    When it's phosphorylated by PKA, levels of calcium stored in the sarcoplasmic reticulum are increased, allowing a higher rate of calcium being released at the next contraction. However, the increased rate of calcium sequestration also leads to an increase in lusitropy. Sensitizing troponin-C to the effects of calcium.

  8. Calcification - Wikipedia

    en.wikipedia.org/wiki/Calcification

    Calcification of soft tissue (arteries, cartilage, heart valves, [1] [2] etc.) can be caused by vitamin K 2 deficiency or by poor calcium absorption due to a high calcium/vitamin D ratio. This can occur with or without a mineral imbalance. A common misconception is that calcification is caused by excess amount of calcium in diet. Dietary ...

  9. Calcium sparks - Wikipedia

    en.wikipedia.org/wiki/Calcium_sparks

    Type 2 – found mainly in the heart; Type 3 – found mainly in the brain; Opening of the channel allows Ca 2+ to pass from the SR, into the cell. This increases the local Ca 2+ concentration around the RyR, by a factor of 10. [4] Calcium sparks can either be evoked or spontaneous, as described below. Figure 1: An evoked calcium spark, in a ...

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