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This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, [13] and many pathogens have evolved methods to evade attacks by phagocytes. [14]
The primary function of lymph nodes is the filtering of lymph to identify and fight infection. In order to do this, lymph nodes contain lymphocytes, a type of white blood cell, which includes B cells and T cells. These circulate through the bloodstream and enter and reside in lymph nodes. [26] B cells produce antibodies.
In immunology, the mononuclear phagocyte system or mononuclear phagocytic system (MPS) also known as the macrophage system is a part of the immune system that consists of the phagocytic cells [1] located in reticular connective tissue. The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen.
Lymph nodes of the lungs: The lymph is drained from the lung tissue through subsegmental, segmental, lobar and interlobar lymph nodes to the hilar lymph nodes, which are located around the hilum (the pedicle, which attaches the lung to the mediastinal structures, containing the pulmonary artery, the pulmonary veins, the main bronchus for each side, some vegetative nerves and the lymphatics) of ...
[41] [42] Although macrophages are also found in secondary lymphoid organs like the lymph nodes, they do not reside in T cell zones and are not effective at activating naïve T helper cells. [41] The macrophages in lymphoid tissues are more involved in ingesting antigens and preventing them from entering the blood, as well as taking up debris ...
A lymph node showing afferent and efferent lymphatic vessels Regional lymph nodes. A lymph node is an organized collection of lymphoid tissue, through which the lymph passes on its way back to the blood. Lymph nodes are located at intervals along the lymphatic system.
Lymphatic vessels carry lymph, a colorless, watery fluid originating from interstitial fluid (fluid in the tissues) which is squeezed out of the blood vessels. The lymphatic system transports infection-fighting cells called lymphocytes , is involved in the removal of foreign matter and cell debris by phagocytes and is part of the body's immune ...
Follicular dendritic cells (FDC) are cells of the immune system found in primary and secondary lymph follicles (lymph nodes) of the B cell areas of the lymphoid tissue. [1] [2] [3] Unlike dendritic cells (DC), FDCs are not derived from the bone-marrow hematopoietic stem cell, but are of mesenchymal origin. [4]
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