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Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. [7] [8] It is also used off-label to control sarcoptic mange and demodectic mange. [8] Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin ...
While dogs are a natural host for D. immitis, cats are atypical hosts. Because of this, differences between canine and feline heartworm diseases are significant. The majority of heartworm larvae do not survive in cats, so unlike in dogs, a typical infection in cats is two to five worms.
Some of Merial's most popular products are Frontline, Heartgard, NexGard, Ivomec, PureVax and Previcox. In October 2009, Merial announced it was investing 70 million US$ at its poultry vaccines plant in Nanchang Hi-tech Development Zone, China.
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
Doramectin, sold under the brand name Dectomax among others, is a veterinary medication approved by the US Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice, and mange mites in cattle.
The melanistic mask is caused by the M264V allele (known as E M) at the melanocortin 1 receptor (MC1R) locus, also known as the extension locus. [1] [2] It is completely dominant to the other alleles of the gene, and causes the melanocyte-stimulating hormone to bind to and activate melanocortin 1 receptors (located on melanocytes) in the mask's area, causing those melanocytes to produce ...
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