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The equivalent doses and relative potencies of hydrocortisone compared to various other synthetic corticosteroids have also been reviewed and summarized. [13] The endogenous production rate of cortisol is approximately 5.7 to 9.9 mg/m 2 per day, which corresponds to an oral hydrocortisone dose of approximately 15 to 20 mg/day (for a 70-kg person).
The strength of topical hydrocortisone products ranges from 0.1% to 2.5%, which means there could be 1 mg to 25 mg hydrocortisone in 1g of the products. [12] Some formulations for topical hydrocortisone include hydrocortisone 0.5% cream or ointment, hydrocortisone 1% cream or ointment, and hydrocortisone 2.5% cream or ointment. [ 34 ]
Emergent intramuscular dosing can be given if child is not tolerating oral medications or unable to get IV within 15 minutes. IM hydrocortisone sodium succinate doses are: [3] 25 mg for child 3 years and younger; 50 mg for children >3 yrs – 12 years; 100 mg for children 12 years and older.
Hydrocortisone valerate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It can be used as a medicine to treat itching, swelling, and other skin conditions. It can be used as a medicine to treat itching, swelling, and other skin conditions.
Side effects may occur from sudden discontinuation and prolonged, continuous use can lead to skin thinning. [2] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [3] [4] [5]
Hydrocortisone cream is a type of topical glucocorticoid that is ... [20 ] Cautions. Use in children ... a smaller dose of topical glucocorticoid is required by ...
Hydrocortisone sodium succinate, sold under the brand name Solu-Cortef among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. [ 3 ] Hydrocortisone sodium succinate was approved for medical use in the United States in 1955.
Then change to oral hydrocortisone or cortisone as a single morning dose, and gradually decrease by 2.5 mg each week. When the morning dose is less than replacement, the return of normal basal adrenal function may be documented by checking 0800 cortisol levels prior to the morning dose; stop drugs when 0800 cortisol is 10 μg/dl.