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Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle . [ 1 ] It evaluates many heart conditions, such as coronary artery disease (CAD), [ 2 ] hypertrophic cardiomyopathy and heart wall motion abnormalities.
Thallium-201 is synthesized by the neutron activation of stable thallium in a nuclear reactor, [18] [19] or by the 203 Tl(p, 3n) 201 Pb nuclear reaction in cyclotrons, as 201 Pb naturally decays to 201 Tl afterwards. [20] It is a radiopharmaceutical, as it has good imaging characteristics without excessive patient radiation dose.
Scanning is time-consuming, and it is essential that there is no patient movement during the scan time. Movement can cause significant degradation of the reconstructed images, although movement compensation reconstruction techniques can help with this. A highly uneven distribution of radiopharmaceutical also has the potential to cause artifacts.
Scintigraphy (from Latin scintilla, "spark"), also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by gamma cameras, which are external detectors that form two-dimensional images [1] in a process similar to the ...
The radioisotope thallium-201 (as the soluble chloride TlCl) is used in small amounts as an agent in a nuclear medicine scan, during one type of nuclear cardiac stress test. Soluble thallium salts (many of which are nearly tasteless) are highly toxic and they were historically used in rat poisons and insecticides. Because of their nonselective ...
The thallium was slipped into bottles of Coca-Cola at the Carr and Trepal homes. [27] Thallium was the poison of choice for Saddam Hussein to use on dissidents, which even allowed for them to emigrate before dying. [28] In 1995, Zhu Ling was the victim of an unsolved attempted thallium poisoning in Beijing, China.
Technetium (99m Tc) sestamibi (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging.The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands.
A ventilation/perfusion lung scan, also called a V/Q lung scan, or ventilation/perfusion scintigraphy, is a type of medical imaging using scintigraphy and medical isotopes to evaluate the circulation of air and blood within a patient's lungs, [1] [2] in order to determine the ventilation/perfusion ratio.