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Gilbert syndrome (GS) is a syndrome in which the liver of affected individuals processes bilirubin more slowly than the majority. [1] Many people never have symptoms. [ 1 ] Occasionally jaundice (a slight yellowish color of the skin or whites of the eyes) may occur.
According to the Mayo Clinic, Gilbert syndrome is a common and harmless liver condition caused by a modified gene inherited from parents.
Joey Graziadei. ABC/Christopher Willard Joey Graziadei has officially addressed the comments about his “yellow eyes.” “Hi everyone, I hope you are having a beautiful day,” Joey, 28, said ...
In high school, Graziadei was diagnosed with Gilbert's syndrome. [20] On November 12, 2023, Graziadei became engaged to Kelsey Anderson, a contestant on his season of The Bachelor. [21] This was chronicled in the season finale, which aired on March 25, 2024. [22]
Gilbert syndrome is inherited in both autosomal dominant and autosomal recession nature. Crigler-Najjar syndrome is much more severe and presents in newborns. Crigler-Najjar syndrome is the complete or near complete inactivity absence of UGT1A1 activity a more severe unconjugated hyperbilirubinemia compared to Gilbert Syndrome. [2]
Gilbert Syndrome, a hereditary disease affecting 5% of the US population, leads to stress-induced mild hyperbilirubinemia. [9] The mutated UGT1 gene produces defective UGT1A1 enzymes vital for bilirubin conjugation.
‘At the end of the day, I am told that I am healthy,’ Graziadei says
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