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In medicine, tapering is the practice of gradually reducing the dosage of a medication to reduce or discontinue it. Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug.
The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.
All opioids, both recreational drugs and medications, when reduced or stopped, can lead to opioid withdrawal symptoms. When withdrawal symptoms are due to recreational opioid use, the term opioid use disorder is used, whereas when due to prescribed medications, the term prescription opioid use disorder is used. [3]
The documentary centers on the opioid epidemic, specifically its effect on Huntington, West Virginia, where the overdose rate is 10 times the US average. [2] It follows police, judges, and local nonprofits attempting to help people who struggle with opioid addiction and bring them to recovery as the city grips with a growing number of heroin and prescription painkiller overdoses, and ...
Craig Barritt/Getty Images Bryan Greenberg’s inspiration for his new movie, Junction, came from a personal struggle. “I went in for routine surgery and I got prescribed OxyContin and I became ...
Dopesick focuses on "the epicenter of America's struggle with opioid addiction" across the U.S. on how individuals and families are affected by it, on the alleged conflicts of interest involving Purdue Pharma and various government agencies such as the Food and Drug Administration and the United States Department of Justice, and finally, on the legal case against Purdue Pharma and their ...
The letter reported on an examination of medical files of patients who had been hospitalized and treated with small doses of opioids.The authors concluded that of the 11,882 patients who received at least one narcotic drug, only four of them had developed a "reasonably well documented" addiction among patients who had no history of addiction.
Approximately 15–50% of people who suddenly stop an antidepressant develop antidepressant discontinuation syndrome. [7] [2] [3] [4] The condition is generally not serious, [2] though about half of people with symptoms describe them as severe. [4] Many restart antidepressants due to the severity of the symptoms. [4]