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Cellulitis is usually [9] a bacterial infection involving the inner layers of the skin. [1] It specifically affects the dermis and subcutaneous fat. [1] Signs and symptoms include an area of redness which increases in size over a few days. [1] The borders of the area of redness are generally not sharp and the skin may be swollen. [1]
[8] [7] In rare cases, the infection can progress into necrotizing fasciitis, a serious and potentially fatal infection. [9] Erysipelas, a bacterial infection which primarily affects superficial dermis, and often involves superficial lymphatics. [10] Unlike cellulitis, it does not affect deeper layers of the skin.
Infections which are in the deep tissues (necrotizing cellulitis, fasciitis and myositis) often include Clostridium spp., S. pyogenes or polymicrobic combinations of both aerobic and anaerobic bacteria. Gas in the tissues and putrid-like pus with a gray thin quality are often found in these infections, and they are frequently associated with a ...
In contrast to cellulitis, erysipelas is a bacterial infection involving the more superficial layers of the skin, present with an area of redness with well-defined edges, and more often is associated with a fever.
Loss of the skin leaves patients vulnerable to infections from fungi and bacteria, and can result in sepsis, the leading cause of death in the disease. [13] Death is caused either by infection or by respiratory distress which is either due to pneumonia or damage to the linings of the airway. Microscopic analysis of tissue (especially the degree ...
An estimated 700 million GAS infections occur worldwide each year. While the overall mortality rate for these infections is less than 0.1%, over 650,000 of the cases are severe and invasive, and these cases have a mortality rate of 25%. [4] Early recognition and treatment are critical; diagnostic failure can result in sepsis and death.
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Necrosis (from Ancient Greek νέκρωσις (nékrōsis) 'death') is a form of cell injury which results in the premature death of cells in living tissue by autolysis. [1] The term "necrosis" came about in the mid-19th century and is commonly attributed to German pathologist Rudolf Virchow , who is often regarded as one of the founders of ...