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The Epstein–Barr virus (EBV) is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. EBV is a double-stranded DNA virus. [2] Epstein–Barr virus (EBV) is the first identified oncogenic virus, or a virus that can cause cancer. EBV establishes permanent infection in humans.
Epstein Barr virus capsid antigens (VCA) are any sections of the viral capsid that the hosts' antibodies bind to. The hosts, or individuals infected with the virus, will produce antibodies to target these Epstein Barr viral capsid antigens. [3] IgG VCA antibodies will be produced during the early stage of the EBV infection.
The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV
These cases as well as asymptomatic and more severe cases of EBV infection are diagnosed definitively as EBV-associated by finding during the initial infection period the Epstein–Barr virus, IgM antibody to EBV viral-capsid antigen (VCA-IgM), IgG antibody to VCA (IgG-VCA), and IgG antibody to EBV viral-capsid antigen (EBNA1-IgG) in the blood ...
This photomicrograph depicts leukemia cells that contain Epstein–Barr virus using a FA staining technique. Epstein–Barr virus, EBV, is a member of the Herpesvirus family, and is one of the most common human viruses. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time.
Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...