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Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [9] It has also been used in alcohol dependence and essential tremor . [ 9 ]
Topiramate: Topiramate is an anticonvulsant approved for the management of epileptic seizures and used off label in the treatment of alcohol use disorder. It modulates GABA neurotransmission, and inhibits glutamate receptors, reducing cravings for alcohol and alcohol use.
[1] [2] The reaction has been variously termed a disulfiram-like reaction, alcohol intolerance, and acetaldehyde syndrome. [ 3 ] The prototypical drug of this group is disulfiram (brand name Antabuse), which acts as an acetaldehyde dehydrogenase inhibitor , preventing the metabolism of acetaldehyde into acetic acid , and is used in the ...
There are several FDA-approved weight loss drugs, including semaglutide, orlistat, phentermine-topiramate, naltrexone-bupropion and liraglutide. Metformin is another common medication used off ...
Alcohol use is a major contributing factor for head injuries, motor vehicle injuries (27%), interpersonal violence (18%), suicides (18%), and epilepsy (13%). [198] Beyond the financial costs that alcohol consumption imposes, there are also significant social costs to both the alcoholic and their family and friends. [67]
Qsymia is a combo of topiramate and phentermine, which is an appetite suppressant. You take one tablet each morning. ... Avoid caffeine, large meals, and alcohol before bed. Make your bedroom a ...