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Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [ 3 ] [ 4 ] Generally it is used together with dietary changes and a statin . [ 5 ]
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug.In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [1]
On rare occasions, ezetimibe may cause cholecystitis, pancreatitis, elevation of serum transaminase level and rhabdomyolysis. As hepatic impairment hinders the rate of ezetimibe metabolism by the liver, ezetimibe is not recommended in individuals with moderate or severe hepatic insufficiency due to prolonged systemic exposure to the drug. [19]
Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol. [ 6 ] [ 7 ] In some countries it is sold as a kit or a pack containing two distinct pills.
Bempedoic acid/ezetimibe, sold under the brand name Nexlizet among others, is a fixed-dose combination medication used for the treatment of high cholesterol. [1] [3] It is a combination of bempedoic acid and ezetimibe. [1] [2] The most common side effects are hyperuricemia (high blood levels of uric acid) and constipation. [2]
The US Food and Drug Administration has approved Zepbound to treat chronic obesity. Dr. Leana Wen explains what people should know about the medication.
An antifungal medication that’s usually used to treat skin infections like athlete's foot, ketoconazole also inhibits 5α-reductase — the enzyme that converts testosterone into DHT.
[17] [18] The medication appears to work equally well regardless of sex, [19] although some sex-related differences in treatment response were described. [ 20 ] If there is an underlying history of cardiovascular disease, it has a significant impact on the effects of statin.