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Saline solution normally contains 0.9% sodium chloride. This article walks you through application instructions based on the intended use.
Saline solution for irrigation. Normal saline (NSS, NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, 308 mOsm/L or 9.0 g per liter. Less commonly, this solution is referred to as physiological saline or isotonic saline (because it is approximately isotonic to blood serum, which makes it a physiologically normal solution).
A retrospective analysis of wound cleanser clinical efficacy and cost-effectiveness focused on polyhexamethylene biguanide solution, Ringer's solution or saline in 112 venous leg ulcer patients. [31] The study group received the polyhexamethylene biguanide solution (n=59) and the control group received either Ringer's solution or saline (n=53).
This is sometimes used to debride wounds, however some training authorities advise against this as it may kill cells which bacteria can then feed on; Irrigation syringe – with catheter tip for cleaning wounds with sterile water, saline solution, or a weak iodine solution. The stream of liquid flushes out particles of dirt and debris.
There are many different ways to prepare PBS solutions, common ones are Dulbecco's phosphate-buffered saline (DPBS) [2] and the Cold Spring Harbor protocol. [3] Some formulations of DPBS do not contain potassium and magnesium, while other ones contain calcium and/or magnesium (depending on whether or not the buffer is used on live or fixed tissue: the latter does not require CaCl 2 or MgCl 2).
For incisional abscesses, it is recommended that incision and drainage is followed by covering the area with a thin layer of gauze followed by sterile dressing.The dressing should be changed and the wound irrigated with normal saline at least twice each day. [4]