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Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [ 2 ]
Valganciclovir is commonly associated with vomiting, abdominal pain, diarrhea, and headache. [2] Other side effects include fever, trouble sleeping, peripheral neuropathy, and retinal detachment.
Version 3.0 also included drug transporter data, drug pathway data, drug pricing, patent and manufacturing data as well as data on >5000 experimental drugs. Version 4.0 was released in 2014. [ 4 ] This version included 1558 FDA-approved small molecule drugs, 155 biotech drugs and 4200 unique drug targets.
List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 ...
FV-100, also known as Cf1743, is an orally available nucleoside analogue drug [1] with antiviral activity. [2] It may be effective against shingles. [3]It was discovered in 1999 in the laboratories of Prof Chris McGuigan, Welsh School of Pharmacy and Prof. Jan Balzarini, Rega Institute, Leuven, Belgium.
RSCB Protein Data Bank "PDB". 166,891 PharmGKB Shriram Center for Bioengineering and Chemical Engineering drugs targets prescribing info curated "PharmGKB". PHAROS Illuminating the Druggable Genome National Institutes of Health drug ligands; targets [9] https://pharos.nih.gov/ 355932 ligands 20412 targets Phenol-Explorer polyphenols found in food
Once you and your plan have spent $5,030 (in 2024) on covered drugs, including your deductible, you enter the "donut hole," where you'll pay 25% of the drug's cost. Catastrophic coverage.
The drug inhibits replication of varicella zoster virus (VZV) – which causes herpes zoster – and herpes simplex virus type 1 (HSV-1), but not HSV-2 which typically causes genital herpes. In vitro , inhibitory concentrations against VZV are 200- to 1000-fold lower than those of aciclovir and penciclovir , theoretically indicating a much ...