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A heart attack can cause arrhythmias, as well as permanent damage to the heart muscle. [25] Coronary ischemia resulting from coronary artery disease also increases the risk of developing heart failure. [10] Most cases of heart failure result from underlying coronary artery disease. [10]
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]
Ischemic cardiomyopathy is a type of cardiomyopathy caused by a narrowing of the coronary arteries which supply blood to the heart. [4] Typically, patients with ischemic cardiomyopathy have a history of acute myocardial infarction, [5] however, it may occur in patients with coronary artery disease, but without a past history of acute myocardial infarction.
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]
But another study defines MACE as "CVD events, admission for HF (heart failure), ischemic cardiovascular [CV] events, cardiac death". [7] Yet another study defined MACE as "CV death, hospitalization for HF, or myocardial infarction (MI)".
Several physical symptoms include shrinkage of one or both kidneys, [19] renovascular hypertension, [20] acute renal failure, [19] progressive azotemia, [19] and acute pulmonary edema. [19] It is a disease with high mortality rate and high morbidity. [21] Failure to treat could cause chronic kidney disease [22] and a need for renal surgery. [23]
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