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Class 3 semaphorins are one of the most versatile semaphorin classes, in which Sema3a is the most studied. During development, semaphorins and their receptors may be involved in the sorting of pools of motor neurons and the modulation of pathfinding for afferent and efferent axons from and to these pools. [ 6 ]
SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.[supplied by OMIM] [ 6 ]
Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene. [ 5 ] SEMA7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI) linkage.
20349 Ensembl n/a ENSMUSG00000063531 UniProt O15041 P70275 RefSeq (mRNA) NM_001178129 NM_012431 NM_011348 RefSeq (protein) NP_001171600 NP_036563 NP_035478 Location (UCSC) n/a Chr 5: 14.08 – 14.31 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Semaphorin 3E is a protein that in humans is encoded by the SEMA3E gene. Function Semaphorin are a large family of conserved secreted and ...
The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.
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The SEMA3A gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain.This secreted Semaphorin-3A protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites.
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