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  2. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]

  3. Depression and immune function - Wikipedia

    en.wikipedia.org/wiki/Depression_and_immune_function

    In addition to evidence suggesting that inflammation is not sufficient for the development of major depression, evidence for a lack of complete overlap also comes from findings that depression often occurs without existing immune challenges, with social adversity appearing to cause depression without the requirement of underlying inflammation.

  4. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Specialty Psychiatry ...

  5. Depression (mood) - Wikipedia

    en.wikipedia.org/wiki/Depression_(mood)

    Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people worldwide, as of 2020. [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]

  6. Animal models of depression - Wikipedia

    en.wikipedia.org/wiki/Animal_models_of_depression

    It is difficult to develop an animal model that perfectly reproduces the symptoms of depression in patients. It is generic that 3 standards may be used to evaluate the reliability of an animal version of depression: the phenomenological or morphological appearances (face validity), a comparable etiology (assemble validity), and healing similarities (predictive validity).

  7. Depression (physiology) - Wikipedia

    en.wikipedia.org/wiki/Depression_(physiology)

    In physiology and medicine, depression [1] refers to a lowering, in particular a reduction in a specific biological variable or the functions of an organ. It is the opposite of elevation. For example, it is possible to refer to "depressed thyroid function" or to a depression of blood flow in a particular area. Further examples:

  8. Tripartite Model of Anxiety and Depression - Wikipedia

    en.wikipedia.org/wiki/Tripartite_Model_of...

    Physiological hyperarousal is defined by increased activity in the sympathetic nervous system, in response to threat. [11] Physiological hyperarousal is unique to anxiety disorders. [ 2 ] [ 12 ] Some symptoms of physiological hyperarousal include: shortness of breath, feeling dizzy or lightheaded, dry mouth, trembling or shaking, and sweaty palms.

  9. Behavioral theories of depression - Wikipedia

    en.wikipedia.org/wiki/Behavioral_theories_of...

    The framework suggests that a lack of self-acceptance lies at the root of depression and that one can heal their own depression if they (a) keep an alert eye to their own emotional state (i.e., identify feelings of shame or depression) and (b) upon identification, take reparative action: undergo a context shift and immerse oneself in a new ...

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