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Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be ...
Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]
The pathogen primarily affects the kidneys and brain, causing neurological disorders. The most common symptom is a tilted head. Fenbendazole, an antiparasitic drug, can be used to combat the pathogen and prevent new infections. If clinical symptoms occur, treatment must be extended by administering antibiotics and supportive measures. The ...
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
[1] [2] Oxfendazole is the sulfoxide metabolite of fenbendazole. Oxfendazole is an anthelmintic (wormer) compound used in veterinary practice. It comes under the chemical class of the benzimidazoles. This drug is barely used in horses, [3] goats, sheep, and cattle. It is very scarcely applied on dogs and cats.
Compared with Lilly’s Zepbound (tirzepatide), the once-daily experimental drug would be simpler to produce.
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