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The term "xenobiotics", however, is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because xenobiotics are understood as substances foreign to an entire biological system, i.e. artificial substances, which did not exist in nature before their synthesis by humans.
Cytochrome P450 oxidases are important enzymes in xenobiotic metabolism.. Xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as drugs and poisons.
Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology caused by teratogens and also in pharmacology and toxicology.
Xenobiotica is a peer-reviewed medical journal that publishes comprehensive research papers on all areas of xenobiotics. It is published by Informa plc and covers six main areas: General xenobiochemistry , including in vitro studies concerned with the metabolism , disposition and excretion of drugs, and other xenobiotics, as well as the ...
Description: This book explained Dalton's theory of atoms and its applications to chemistry. Importance: The book was one of the first to describe a modern atomic theory, a theory that lies at the basis of modern chemistry. [3]: 251 It is the first to introduce a table of atomic and molecular weights.
Journal of Xenobiotics is a peer-reviewed open-access scientific journal covering various aspects of xenobiotics research. It is published by MDPI and was established in 2011. The journal publishes research articles, reviews, and commentaries related to xenobiotics research, including biochemistry , toxicology , pharmacology , and the ...
Free radical mechanisms in tissue injury. Lipid peroxidation induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination). Antioxidants play a crucial role in mitigating lipid peroxidation by neutralizing free radicals, thereby halting radical chain reactions. Key antioxidants include vitamin C and vitamin E. [8]
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]