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Malaria prophylaxis is the preventive treatment of malaria. ... it is important to weigh the risk of infection against the risks and side effects associated with the ...
The neuropsychiatric side effects of the antimalarial drug mefloquine are well documented. They include anxiety, depression, hallucinations, acute psychosis, and seizures. The incidence of these side effects is 1 in 13,000 with prophylactic use and 1 in 250 with therapeutic use.
In prophylactic therapy, 100 mg (adult dose) of doxycycline should be given every day during exposure to malaria. The most commonly experienced side effects are permanent enamel hypoplasia (although this is only relevant during the period of tooth development during the first decade of life), transient depression of bone growth ...
Side effects include diarrhea, rash, itchiness, headache, and hair loss. [3] [1] Rarely a severe allergic reaction or rash such as toxic epidermal necrolysis, may occur. [1] It is not generally recommended in people with a sulfonamide allergy or significant liver or kidney disease. [3] It works by blocking malaria's ability to use folinic acid. [1]
Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. [2] It is an alternative treatment for Pneumocystis pneumonia together with clindamycin. [2] [3] It is taken by mouth. [2] Common side effects include nausea, vomiting, and stomach cramps.
Piperaquine is an antimalarial drug, a bisquinoline first made in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based antimalarials became available.
Serious side effects may include anaphylaxis, Stevens–Johnson syndrome, hallucinations, and liver problems. [3] [4] Side effects are generally mild. [5] It is unclear if use during pregnancy or breastfeeding is safe for the baby. [6] It is not recommended to prevent malaria in those with poor kidney function. [4]
Proguanil, also known as chlorguanide and chloroguanide, is a medication used to treat and prevent malaria. [3] [4] It is often used together with chloroquine or atovaquone.[4] [3] When used with chloroquine the combination will treat mild chloroquine resistant malaria. [3]