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Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. [ 6 ] [ 4 ] [ 5 ] Symptoms may include muscle pains , weakness, vomiting , and confusion .
These systemic effects are caused by a traumatic rhabdomyolysis. As muscle cells die, they absorb sodium, water, and calcium; the rhabdomyolysis releases potassium, myoglobin, phosphate, thromboplastin, creatine, and creatine kinase. [citation needed] Crush syndrome can directly come from compartment syndrome, if the injury is left untreated. [8]
Rhabdo symptoms can appear any time after a muscle injury, and for some start several days later. You might have one or more of these symptoms if you develop rhabdo, in which case you should ...
Treatment for metastatic rhabdomyosarcoma has not changed over the last three decades and five-year survival outcomes in those with high-risk rhabdomyosarcoma remain less than 40%. [37] In terms of overall survival, metastatic rhabdomyosarcoma remains at 21% while recurrent rhabdomyosarcoma remains at 30%. [32]
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RMS can occur in almost any soft-tissue site in the body; the most common primary sites are genitourinary (24%), parameningeal (16%), extremity (19%), orbit (9%), other head and neck (10%), and miscellaneous other sites (22%). [14] RMS often presents as a mass, but signs and symptoms can vary widely depending on the site of the primary tumor.
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However, in some low-risk individuals, supervision by a medical professional is not required as long as the individual follows up with weekly checkups. [23] Proper hydration prior to performing physical activity and performing exercise in cool, dry environments may reduce the chances of developing a reoccurring episode of ER. [ 23 ]