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The effective population size (N e) is the size of an idealised population that would experience the same rate of genetic drift as the real population. [1] Idealised populations are those following simple one- locus models that comply with assumptions of the neutral theory of molecular evolution .
It is a measure of the "population mutation rate" (the product of the effective population size and the neutral mutation rate) from the observed nucleotide diversity of a population. θ = 4 N e μ {\displaystyle \theta =4N_{e}\mu } , [ 3 ] where N e {\displaystyle N_{e}} is the effective population size and μ {\displaystyle \mu } is the per ...
In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of one parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size ...
Kimura and Ohta (1969) showed that a new mutation that eventually fixes will spend an average of 4N e generations as a polymorphism in the population. [2] Average time to fixation N e is the effective population size, the number of individuals in an idealised population under genetic drift required to produce an equivalent amount of genetic ...
This relationship between the effective population size and selection efficiency was evidenced by genomic studies of species including chimpanzee and human [45] and domesticated species. [46] In small populations (e.g., a population bottleneck during a speciation event), slightly deleterious
where u is the mutation rate, and N e is the effective population size. The effective number of alleles n maintained in a population is defined as the inverse of the homozygosity, that is = = + which is a lower bound for the actual number of alleles in the population. If the effective population is large, then a large number of alleles can be ...
The effective population size (N e) is defined as "the number of breeding individuals in an idealized population that would show the same amount of dispersion of allele frequencies under random genetic drift or the same amount of inbreeding as the population under consideration."
In a population with a constant effective population size with 2N e copies of each locus, there are 2N e "potential parents" in the previous generation. Under a random mating model, the probability that two alleles originate from the same parental copy is thus 1/(2 N e ) and, correspondingly, the probability that they do not coalesce is 1 − 1 ...